Health Economics: Concepts, Economic Evaluation and Cost Analysis

 

Health Economics: Concepts, Economic Evaluation and Cost Analysis

Introduction

Health is not only a matter of medical treatment. It is also an economic issue because the resources available for health and health care are limited, while the needs and expectations of individuals and populations are extensive. Health economics applies economic thinking to the organization, allocation, and use of these scarce resources in the health sector.

Economics is the science of scarcity. It analyzes how choices are structured and prioritized to maximize welfare within constrained resources. It is also concerned with the distribution of scarce resources, commonly known as goods and services, across a population. The consequences of resource scarcity and the use of scarce resources to satisfy human wants and needs are therefore central to economic analysis.

Two broad approaches are commonly distinguished in economics. Positive economics seeks to establish cause-and-effect relationships in a scientific manner, whereas normative economics is concerned with establishing the means by which socially desirable outcomes can be achieved.

What Is Health?

Health is broader than the mere absence of disease or infirmity. According to the World Health Organization's constitution, health is a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity.

In health economic evaluation, health status is considered according to some measure. This makes it possible to examine health outcomes in economic terms and to compare the consequences of alternative health-related decisions.

What Is Health Economics?

Health economics is the study of the distribution of health care. It is a branch of economics concerned with issues related to efficiency, effectiveness, value, and behavior in the production and consumption of health and health care.

Health economics is also concerned with the allocation of resources within the health system in the economy and with the functioning of the health care market. It involves the formal analysis of the costs, benefits, management, and consequences of health and health care and applies economic theory to phenomena and problems associated with health and health care.

More broadly, health economics studies how scarce resources are allocated among alternative uses for the care of sickness and the promotion, maintenance, and improvement of health. This includes the study of how health care and health-related services, their costs and benefits, and health itself are distributed among individuals and groups in society. Health economics can therefore be understood as the application of the theories, concepts, and techniques of economics to the health sector.

Basic Concepts in Health Economics

Resources and Scarcity

Resources are limited, while human needs and wants are extensive. Scarcity creates the need for choices about how resources should be allocated. In health economics, scarcity is closely associated with opportunity cost, efficiency, and the production of health.

Opportunity cost represents the value of the next best alternative that is forgone when resources are committed to a particular health intervention or service. Efficiency concerns how well available resources are used to achieve health-related objectives. These concepts are fundamental to decisions within the health care market.

Macroeconomics and Health

Health economics also has a relationship with macroeconomics. The economy's level of output, the level of national income, and the general price level are among the macroeconomic factors that can influence the health sector.

Economic conditions affect the resources available for health care and can influence the organization, financing, and use of health services. Health economics therefore cannot be considered independently of the wider economic environment.

Microeconomics and Health

Microeconomics is the study of the economic behavior of individual decision-making units such as consumers, resource owners, and business firms in a free enterprise economy. In health economics, microeconomic analysis can be examined through market surveys, pilot studies, and feasibility studies.

Health microeconomics is concerned with how individuals choose, minimize costs, or maximize profit or utility within a given health care system and within a set of rules and prices.

Components and Scope of Health Economics

The scope of health economics includes the meaning and scope of health economics itself, determinants of health, demand for health and health care, supply of health care, and health care markets.

It also includes the relationship between economic growth and health, health sector budgeting and planning, national health systems, equity in health outcomes and health care, and international health.

These areas connect economic decisions with the organization and performance of health systems. Health economics therefore extends from individual choices within health care to the planning and financing of national and international health systems.

Need for Health Economics

The need for health economics arises from several developments in health and society. Medical advances have expanded the possibilities for prevention, diagnosis, treatment, and care. At the same time, increases in life expectancy have increased the period over which health services may be required.

Changes in family structure and social norms, advances in health research, higher expectations among people, and increasing public awareness of health also contribute to the need for systematic economic analysis in health.

As health needs and expectations increase while resources remain constrained, decisions about priorities, resource allocation, and the value of different health interventions become increasingly important.

Importance of Health Economics

Health economics helps formulate health services and establish the true costs of delivering health care. These costs can include not only direct expenditures but also other real costs, such as patients' time and loss of output elsewhere in the system.

It also helps evaluate the relative costs and benefits of particular policy options. Economic variables such as user charges, time, and distance costs of accessibility can be examined to understand their effects on the utilization of health services.

Health economics is relevant to health policy and economic development. It helps identify and measure health and diseases, identify basic needs, determine the determinants of growth and economic development, and examine elements of health expenditure through macroeconomics.

It also helps determine the economic characteristics of health care and health-related activities, identify sources of health care financing such as social accounting systems and self-financing insurance, and analyze determinants of demand, individual and supplier-induced behavior, time, cost, and health payment systems.

Further applications include determining physical resources and costs, estimating short-term and long-term cost curves, examining the labor market and the demand and supply of health workers, studying remuneration and other determinants of behavior and productivity, and supporting budgeting, accounting, and inventory management.

Major Tasks of Economics in Health Care

Economic analysis in health care can be organized around three major tasks: descriptive quantification, explanatory or predictive analysis, and evaluative analysis.

Descriptive quantification focuses on measuring and describing relevant health and economic conditions. Explanatory or predictive analysis examines relationships and helps understand or anticipate outcomes. Evaluative analysis compares alternative courses of action in terms of their costs and consequences to support decisions.

Features of Health Economics

Health and medical care are considered economic goods, and health may be viewed in relation to both private and public goods. Measurement of health is also an important part of economic analysis.

Health economics considers the stock of health and the investment aspects of health. It also examines losses associated with ill health, the resource costs of different diseases, and the effects of health and medical care provision.

Planning of health and medical care, choice of technology in the health care system, and provision of equity in health outcomes and health care are also important features of the field.

Areas of Health Economics

Health economics covers the economic aspects of the relationship between health status and productivity and the financial aspects of health care services. It also addresses economic decision-making in health and medical care institutions and the planning of health development and related activities.

Factors Influencing Health Economics

Health economics is influenced by several characteristics of the health sector. These include extensive government intervention, intractable uncertainty in several dimensions, information asymmetry, barriers to entry, and externalities together with the presence of a third-party agent.

These characteristics make health care different from many ordinary markets and create a need for careful economic analysis when resources and policies are evaluated.

Tools Used in Economic Analysis

Economic analysis uses economic variables, relationships between economic variables, graphical representation of relationships, and the direction of those relationships. These tools help describe economic conditions, examine how variables are connected, and evaluate the consequences of changes in costs, resources, prices, and outcomes.

Economic Evaluation

Economic evaluation is the comparative analysis of alternative courses of action in terms of both their costs and consequences in order to assist policy decisions.

A systematic economic evaluation therefore requires a clear study question, identification and measurement of costs and health effects, appropriate adjustment for timing, adjustment for uncertainty, and ultimately a decision.

Steps in Economic Evaluation

The process begins by deciding upon the study question. The costs and health effects are then assessed, followed by adjustment for timing and adjustment for uncertainty. The final stage is making a decision based on the results.

The purpose is not simply to calculate costs. The objective is to compare alternatives in a structured way so that available resources can be directed toward interventions that provide appropriate value and health outcomes.

Types of Economic Evaluation

Several forms of economic evaluation are used in health economics. These include cost-benefit analysis, cost-minimization analysis, cost-utility analysis, and cost-effectiveness analysis.

The methods differ mainly in how costs and outcomes are measured and compared. Cost-benefit analysis expresses both costs and outcomes in monetary terms. Cost-effectiveness analysis expresses outcomes in natural health units. Cost-utility analysis expresses outcomes in utility-based measures such as quality-adjusted life years. Cost-minimization analysis is used when the outcomes of the alternatives are assumed to be equal and the comparison is therefore based on costs.

Cost Analysis

Cost analysis is a resource tool for financial management in a hospital or department. It is an economic evaluation technique involving the systematic collection, categorization, and analysis of program or intervention costs and the cost of illness.

Cost analysis can be used as an evaluation method when only one program is being assessed, when information about program effectiveness is not available, or when the interventions being assessed and compared are equally effective.

Its objectives include assessing the efficiency and effectiveness of functions and their cost implications, improving policy relevance and utility through assessment and planning and avoidance of wasteful expenditure in the hospital, and allowing researchers to achieve cost minimization for the programs under consideration.

Cost analysis is also a tool for planning and cost projection. It can be used to assess the efficiency of a program, assess priorities, support accountability, and assess equity.

Principles of Cost Analysis

A sound cost analysis should make the analytic perspective explicit and describe the anticipated benefits. It should specify the components of costs, discount to adjust for differential timing, perform a sensitivity analysis, and calculate measurements of efficiency.

A framework for cost analysis begins with identifying and defining the problem, defining the alternatives, defining the audience, defining the perspective, defining the time frame, determining the time frame and analytic horizon, and choosing an appropriate format or methodology.

The basic process then involves defining the program, treatment, or technology to be analyzed; developing a framework for cost analysis; describing the objectives of the analysis; selecting the type of cost analysis; and designing the methodology. The principles of cost analysis are applied, study outcomes are described, a cost inventory is developed, and a cost summary is prepared.

Resources used are measured and evaluated, after which cost analysis results such as total cost, average cost, and marginal cost are calculated. Sensitivity analysis and discounting are also applied where appropriate.

Total Cost

The total cost of a program or intervention is derived by adding all the costs incurred in producing a given level of output. It includes the costs of personnel, supplies, and equipment identified in the cost inventory.

The total cost can be represented as the sum of the quantity of each resource multiplied by the value of that resource:

TC = Quantity of resource 1 × value of resource 1 + … + Quantity of resource n × value of resource n

Average Cost

Average cost is the cost per unit of output, such as the cost per patient treated or the cost per child immunized. It is calculated by dividing total cost by the number of participants or other relevant intervention units.

AC = TC / Q

Here, Q represents the units of output.

Marginal Cost

Marginal cost is the resource cost associated with producing one additional or one less unit within the same intervention or program. It can be expressed as the change in total costs divided by the change in quantity produced.

MC = Change in total costs / Change in quantity produced

or

MC = (TC′ − TC) / (Q′ − Q)

Here, TC′ is total cost at a higher output level, TC is total cost at a lower output level, Q′ is the higher level of output, and Q is the lower level of output.

Health Valuation Methods

Health valuation can involve the cost-of-illness method and non-market valuation methods. Non-market valuation methods include revealed preference methods and stated preference methods.

Revealed Preference Method

Hedonic pricing is based on the principle that the prices consumers pay or receive depend on characteristics of the person that can be objectively measured. The relationship can be represented as:

W = f(q, e, ex, a, g)

Here, W is the wage rate; q is a measure of qualification; e is experience; ex is a measure of experience; a is age; and g is gender.

Hedonic pricing can also be used to examine how characteristics of a product contribute to its unit price. For example, the unit price of a personal computer can be related to characteristics such as display size, HDD memory capacity, type of optical drive, bundled software, CPU memory capacity, and other features.

Averting Behavior Method

The value of a small change in health status can be measured by the amount of money a person is willing and able to spend on some controlling or preventive device or defensive, or averting, action. This amount of money represents the person's valuation of safety against a perceived risk.

Stated Preference or Contingent Valuation Method

The stated preference or contingent valuation method is a direct method that uses primary surveys to ask persons to place values on an intervention to attain a level of health outcome.

Cost-Benefit Analysis

Cost-benefit analysis is a practical way of assessing the desirability of projects when it is important to take a long view, considering repercussions in the future as well as the near future, and a wide view that allows the side effects of many decisions to be considered. It involves the enumeration and evaluation of all relevant costs and benefits.

Cost-benefit analysis is an economic evaluation technique that measures all positive, or beneficial, and negative, or costly, consequences of an intervention or program in monetary terms.

It is also a practical approach to appraising the desirability of an intervention involving public expenditure in terms of net social gain to society. It uses analytical techniques involving monetary assessment to identify the total costs and benefits of a specific intervention.

Benefits in Cost-Benefit Analysis

Benefits may be direct, indirect, or intangible. When benefits exceed costs, the intervention produces positive net benefits. Net benefits can be expressed as:

NB = B − C > 0

Here, B represents benefits and C represents costs.

Importance of Cost-Benefit Analysis

Cost-benefit analysis is used for determining priorities among various alternative programs or interventions. It provides an estimate of the potential value of undertaking a course of action, such as instituting a new program or intervention or revising an existing one.

It can also be used to compare health-related interventions with activities in other economic sectors. It enables policy makers to determine whether the value of positive consequences exceeds the value of the societal resources required to implement a program.

By estimating and totaling the equivalent monetary value of benefits and costs, cost-benefit analysis helps establish whether projects are worthwhile. It provides a practical basis for deciding whether a change should be made.

Features and Purposes of Cost-Benefit Analysis

Cost-benefit analysis adopts a broad societal perspective because it includes all costs and all benefits. It measures outcomes in monetary terms and assesses the desirability of a program or intervention.

Its purposes include assessing economic efficiency, deciding whether to implement a specific program, and selecting among competing or alternative options.

Principles of Cost-Benefit Analysis

There must be a common unit of measurement in cost-benefit analysis. All benefits and costs of a program or project must be measured in terms of their equivalent monetary value.

The valuations should represent consumers' or producers' valuations, and the valuation of benefits and costs should reflect preferences revealed by choices. Benefits are usually measured by market choices. The marginal benefit should be equal to the market price, and the gross benefits of an increase in consumption are represented by the area under the demand curve.

Some measurements of benefits require the valuation of human life. These values can be used to estimate personal costs in terms of increased risk or reduced risk. The alternatives must be explicitly specified and considered in the evaluation, and the impacts of the programs must be defined.

The discounted present value of benefits should exceed the discounted present value of costs. Alternative programs should be compared in terms of their expected benefits and cost ratio to determine which should receive priority for funding.

Advantages of Cost-Benefit Analysis

Cost-benefit analysis helps allocate scarce resources to programs that maximize societal economic benefit. It studies the full economic impact of all potential outcomes of an intervention.

It makes it possible to compare different programs having different health outcomes, as well as health programs with non-health programs. It also allows analysts to examine distributional aspects by considering who will receive the benefits and who will bear the costs.

Drawbacks of Cost-Benefit Analysis

Cost-benefit analysis measures costs and outcomes in monetary terms rather than disease-specific units. A major difficulty is assigning monetary values to all pertinent outcomes, including changes in the length or quality of human life.

The results of cost-benefit analysis are only as good as the assumptions and valuations on which they are based. The process of assigning monetary values to health outcomes can therefore be a significant challenge.

Approaches to Cost-Benefit Analysis

Two approaches identified in the material are the ratio approach and the net benefit approach. The ratio approach relates benefits to costs, whereas the net benefit approach focuses on the difference between benefits and costs.

Procedural Steps in Cost-Benefit Analysis

A cost-benefit analysis begins with defining the problem and identifying the interventions. The audience and perspective are then defined, followed by definition of the time frame and analytic horizon. The discount rate is also defined.

The intervention outcomes are identified as health outcomes, non-health outcomes, and intangible outcomes. These outcomes provide the basis for identifying and assessing the consequences of alternative interventions.

Cost-Effectiveness Analysis

Cost-effectiveness analysis is an economic study design in which the consequences of different interventions are measured using a single outcome, usually in natural units such as life-years gained, deaths avoided, heart attacks avoided, or cases detected. Alternative interventions are then compared in terms of cost per unit of effectiveness.

Cost-effectiveness analysis provides decision-makers with a tool for assessing and potentially improving the performance of health systems. It indicates which interventions provide the highest value for money and helps decision-makers choose interventions and programs that maximize health for the available resources.

Cost-effectiveness analysis examines both the costs and health outcomes of alternative intervention strategies.

Aim and Objectives of Cost-Effectiveness Analysis

The aim of cost-effectiveness analysis is to maximize the level of benefits, or health effects, relative to the level of resources available.

Its objectives include comparing alternative programs with a common health outcome and assessing the consequences of expanding an existing program.

Purposes of Cost-Effectiveness Analysis

Cost-effectiveness analysis can identify the most cost-effective intervention from a group of alternatives and provide empirical justification for a program.

It can also identify and exclude programs that are wasting resources, provide general information on the relative costs and health benefits of different alternatives, and evaluate interventions in terms of efficacy, cost-effectiveness ratio, absolute health gain, and affordability or absolute cost.

Benefits and Drawbacks of Cost-Effectiveness Analysis

Cost-effectiveness analysis is relatively easy to understand and is well suited to decision-making. It provides empirical results that allow decision-makers to compare the costs and consequences associated with alternative programs.

However, data regarding direct costs, such as doctors' or nurses' time and supplies used, and indirect costs, such as a portion of administrative costs and equipment costs, may not be readily available. Cost-effectiveness analysis also does not facilitate comparisons across different diseases when different outcomes have been used.

Cost-effectiveness is only one criterion for judging whether an intervention is effective or desirable. It therefore does not, by itself, capture every consideration involved in a health policy decision.

Measures for Cost-Effectiveness

Two measures identified for cost-effectiveness are the cost-effectiveness ratio (CER) and net health benefits (NHB).

The cost-effectiveness ratio may be considered through the average cost-effectiveness ratio (ACER), marginal cost-effectiveness ratio (MCER), and incremental cost-effectiveness ratio (ICER).

Net health benefits represent the difference between the health outcome and cost divided by the rate of substitution of money for health. The expression given is:

NHB = E − C/A

Elements and Procedural Steps in Cost-Effectiveness Analysis

A cost-effectiveness analysis requires a clear study perspective, time frame, and analytic horizon; an explicitly defined study question; relevant assumptions underlying the study; detailed descriptions of the interventions; existing evidence of intervention effectiveness; proper identification of all relevant costs; and a comprehensive discussion of the results.

The procedural process includes defining the problem, adopting a research strategy, specifying the audience, defining the perspective, specifying the time frame, preparing the analytic horizon, deciding the type of study design, identifying outcome measures or variables, searching for available alternatives, identifying the types of costs to be included, and conducting the analysis.

Cost-Utility Analysis

Utility is the value or worth of a level of health as measured by the preferences of an individual or society. Cost-utility analysis is one form of cost-effectiveness analysis that allows different health outcomes to be compared by measuring them in terms of a single unit, such as the quality-adjusted life year, or QALY.

Cost-utility analysis weighs costs and quality-adjusted health outcomes of each intervention in order to support the decision about which program should be implemented.

Measures of Cost-Utility Analysis

The principal measures identified are quality-adjusted life years (QALY) and disability-adjusted life years (DALY). These measures provide ways of representing health outcomes in a form that can be used in economic evaluation.

Methods of QALY

Methods used to obtain QALY include the health rating method, time trade-off method, standard gamble method, and health index method.

Disability-Adjusted Life Years

The World Health Organization defines disability-adjusted life years, or DALYs, as a health gap measure that extends the concept of potential years of life lost due to premature death to include equivalent years of healthy life lost by virtue of being in states of poor health or disability. In other words, one DALY represents one lost year of healthy life.

DALY is a combined measure of years lived with disability and years of life lost due to premature death.

Measures of DALY

Years of Life Lost (YLL) represents the number of years of life lost due to premature death.

Years Lived with Disability (YLD) represents the number of healthy years lost due to disability from the condition until remission or death.

Together, these components form the basis of the disability-adjusted life year measure.

Advantages of Cost-Utility Analysis

Cost-utility analysis can be used to measure health care costs and interventions and to evaluate the effect of a nursing intervention on patient outcomes when one of the outcomes is quality of life. It can also be used to compare the use of a nursing process management approach with disease process management, such as hypertension management.

Cost-utility analysis can assess cost utility for both medical and nursing interventions and can be used to compare current practice with changes in practice needs.

The cost utility ratio is used for comparing interventions in terms of the cost required to achieve one quality-adjusted life year.

Cost-Minimization Analysis

Cost-minimization analysis is a specific type of analysis in which the outcomes of two or more health care interventions are assumed to be equal. Economic evaluation is therefore based solely on comparative costs, and the result is the least-cost alternative.

Cost-Consequence Analysis

Cost-consequence analysis is a form of cost-effectiveness analysis that compares alternative interventions or programs in which the components of incremental costs, such as additional therapies and hospitalization, and consequences, such as health outcomes and adverse effects, are computed and listed without aggregating the results into a cost-effectiveness ratio.

Cost-consequence analysis provides a means of estimating whether the value of results obtained is worth the investment. Instead of combining costs and effects, all costs and outcomes are reported separately.

Its advantages include simplicity and the ability to evaluate the entire program of care. It allows decision-makers to impute their own values to different costs and consequences, incorporates several outcome measures, and makes the findings relatively easy to interpret. It can also be used to evaluate practice guidelines and disease-state management programs.

A disadvantage is the difficulty of comparing outcomes between different interventions in order to prioritize them.

Conclusion

Health economics provides a systematic framework for understanding how scarce resources are allocated within health systems and how economic principles can be applied to health and health care. It connects questions of resources, scarcity, demand, supply, costs, outcomes, efficiency, effectiveness, value, equity, and policy.

The economic evaluation of health interventions is particularly important because decisions often involve competing alternatives and limited resources. Cost analysis helps identify and measure the resources used. Cost-benefit analysis compares costs and benefits in monetary terms. Cost-effectiveness analysis compares costs with outcomes measured in natural health units. Cost-utility analysis incorporates preferences and measures such as QALY and DALY, while cost-minimization analysis focuses on costs when outcomes are assumed to be equal. Cost-consequence analysis reports costs and consequences separately rather than combining them into a single ratio.

Taken together, these approaches provide different ways to examine the economic consequences of health interventions. Their appropriate use supports more systematic decision-making about health services, programs, technologies, financing, and resource allocation.

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